A Young Woman’s Journey Through Ovarian Cancer & Critically Low Egg Reserve

Conceiving the Impossible: When Every Second Counts

At just 27 years old, Mrs.AN and her husband Mr. M, 28, came to Dr. Hossam Elzeiny seeking help for primary infertility. They had been trying to conceive for two years. Her cycles were regular, but during a routine pelvic ultrasound performed by Dr. Elzeiny himself, he noted something deeply concerning—multiple suspicious ovarian cysts.

Further investigations confirmed the worst: both ovaries were grossly enlarged with hemorrhagic cysts, and CA-125 (tumor marker) levels were alarmingly elevated at 272 u/ml. An urgent MRI revealed large, complex cystic and solid masses on the ovaries, raising high suspicion for malignancy. Despite no signs of metastasis, the situation was critical.

Timely Diagnosis, Life-Saving Surgery
In December 2009, she underwent major surgery that revealed bilateral borderline ovarian tumors with invasive implants extending to the serosa (outer layer) of the uterus. Her CA-125 dropped dramatically to 3 u/ml post-surgery, but her future fertility was now hanging by a thread.

A Delicate Balance: Preserving Fertility in the Face of Cancer
Against all odds, and with oncology clearance, Dr. Elzeiny initiated fertility treatment. In March 2010, using a low-dose agonist (LDR) IVF protocol, 4 eggs were retrieved, 3 fertilized, and 2 embryos transferred. This initial attempt was unsuccessful.

Undeterred, a second embryo transfer resulted in a single successful pregnancy, culminating in a normal vaginal delivery of a healthy 3500g baby girl.

Diminished Ovarian Reserve and a Second Miracle
By April 2011, her AMH had dropped to <1 pmol/L, confirming extremely low ovarian reserve. Despite the grim prognosis, she was determined to expand her family. With Dr. Elzeiny’s personalised care:

  • Sept 2011: 5 eggs retrieved, 2 fertilised, 2 embryos transferred – no pregnancy.
  • Jan 2012: 10 eggs retrieved, 4 fertilised, 2 embryos transferred – again, no pregnancy.
  • Frozen Embryo Transfer: A single Day 3 embryo transfer resulted in another healthy pregnancy and the birth of a 4100g baby girl via vaginal delivery.

Cancer Returns, But So Does Hope
In May 2014, she suffered a recurrence of the serous borderline tumour on her right ovary. Surgery removed the mass, but now she had only one ovary remaining with minimal functional tissue.

Despite oncological recommendations for radical pelvic clearance due to a newly growing cyst on her remaining ovary, she returned to Dr. Elzeiny in hopes of achieving one final pregnancy.

The Most Complex Case Yet
This was not only a medical emergency but an emotional and reproductive crisis. With:

  • One remaining ovary, barely functional
  • Diminished ovarian reserve
  • A history of ovarian cancer and two major surgeries
  • A ticking clock before radical surgery would eliminate her fertility forever

Dr. Elzeiny acted swiftly. His expert scanning, fast-tracked IVF planning, and surgical precision became the defining factors in navigating this final window of opportunity.

Why This Case Proves Dr. Elzeiny Is In a League of His Own

  • He diagnosed the life-threatening tumour before any other doctor – through routine ultrasound
  • He balanced cancer care with fertility preservation, a feat few specialists attempt
  • He delivered two full-term pregnancies despite invasive ovarian cancer and low ovarian reserve
  • He never gave up on her dream of a third child, even when all odds were stacked against her

Are You Facing a Complex Fertility Journey?
Dr. Hossam Elzeiny is renowned for his ability to achieve success in the most challenging cases – from diminished ovarian reserve to fertility-threatening cancers. If you’ve been told “it’s impossible,” it’s time to seek a second opinion from someone who makes miracles possible.

Book your consultation today.
Because when every moment matters, expertise makes all the difference.